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Specialized Chemistry For Drug Discovery 

Computer-Assisted

Drug Discovery

Custom synthesis

The customized synthesis of triterpene and steroid compounds is provided upon request. CHEM4PHARMA conducts quality control of all compounds prepared and provides analytical data, includig 1H and 13C NMR or/ and MS spectra for each compound.

Bioisostere scaffold design

Hit-to-lead optimization

Hemisynthetic libraries creation

Process optimization

Chemical process optimization involving steroid, triterpenoid and other APIs.

We have expertize mainly in:

 

Fluorination reactions

Oxidation reactions

Biocatalysis & Biotransformations

Heterocyclic chemistry

Green pharmaceutical chemistry

Structural elucidation

Specialized services of structural characterization of organic compounds, natural and synthetic, by several techniques including:

NMR 1D ( 1H, 13C, DEPT-45, DEPT-90, DEPT-135)

NMR 2 D (HMQC, HMBC, COSY, NOESY, HSQC)

Mass Spectrometry (Quadrupole/Ion Trap Mass Spectrometer (QIT-MS)

X-Ray Chrystalography

X-Ray Powder Diffraction

Scanning Eletron Microscopy (SEM)

Request informations about our services